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The Impact of AI Assistance on Radiologist Performance and Healthcare Costs in LDCT-Based Lung Cancer Screening

RecruitingNAAges 40 Years - 74 YearsAllThe First Affiliated Hospital of Guangzhou Medica…
NCT06988579 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

AI diagnostic systems show great promise for improving lung cancer screening in community healthcare settings. While not originally designed for primary care, these tools demonstrate capabilities in nodule detection and workflow optimization. However, their effectiveness in resource-limited community centers requires thorough evaluation. This RCT compares AI-assisted versus manual CT interpretation across community health centers. Expert radiologists will establish reference standards, while an independent committee blindly evaluates cases from both groups. The study assesses diagnostic accuracy, operational efficiency, and cost-effectiveness, with blinded analysts resolving discrepancies through consensus to ensure reliable results.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Aged 45-74 years 2. Permanent resident of participating study communities 3. No prior history of lung cancer and no lung cancer screening within the past 3 months 4. Able to comprehend and voluntarily sign informed consent, with willingness to participate in long-term follow-up Exclusion Criteria: 1. Individuals with a confirmed diagnosis of lung cancer 2. Those with severe comorbidities contraindicating CT imaging 3. Inability to understand study protocols or provide informed consent due to cognitive impairment 4. Concurrent participation in other clinical trials that may interfere with study outcomes 5. Unable to comply with follow-up requirements
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What it tests

  • AI
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Where

1 site
the First Affiliated Hospital of Guangzhou Medical University,
Guangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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