AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK

RecruitingPhase 3Ages 18 Years - anyAllKodiak Sciences Inc
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants with Macular Edema Secondary to Inflammation (MESI)

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Macular Edema Secondary to Inflammation (MESI) with a central subfield thickness (CST) of โ‰ฅ400 microns on SD-OCT in Study Eye. * Definitive presence of Intraretinal Fluid and/or Subretinal Fluid on SD-OCT in the Study Eye. * BCVA ETDRS score of โ‰ฅ25 and โ‰ค70 letters (between 20/40 and 20/320 Snellen equivalent) in the Study Eye. * Diagnosis of active or inactive non-infectious intraocular inflammation, acute or chronic in the Study Eye. Exclusion Criteria: * Macular Edema in the Study Eye secondary to diabetic retinopathy, RVO, or wAMD. * Active or suspected ocular or periocular infection in either eye. * Any history of or active occlusive retinal vasculitis in either eye.
๐Ÿ’Š

What it tests

  • KSI-101
  • Sham Comparator
๐Ÿ“

Where

56 sites
AZ Retina & Vitreous Consultants
Phoenix, United States
Research Network Arizona
Scottsdale, United States
California Retina Consultants (Bakersfield)
Bakersfield, United States
Global Research Management, Inc.
Glendale, United States
UCSD/Jacobs Retina Center
La Jolla, United States
UCLA Stein Eye Institute
Los Angeles, United States
California Retina Consultants (Oxnard)
Oxnard, United States
Stanford Byers Eye Institute
Palo Alto, United States

โ€ฆand 48 more on ClinicalTrials.gov.

๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy