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Fertility Limiting Diseases of Pelvic Organs and Their Influence on Receptivity of Endometrial Cavity: Prospective Clinical Trial

Recruitingn/aAges 18 Years - 45 YearsFemaleCharles University, Czech Republic
NCT06991595 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this project, we will characterize the effects of fertility limiting diseases of pelvic organs on the receptivity of the endometrium. The primary aim of the project is the characterization of endometrium in patients with infertility suffering from AD, UF and DE, and compare it with infertile patients with minimal or mild endometriosis but no AD or UF (ETRS group), and with healthy women with only male factor of infertility (CTRL group, controls). The proper infertility treatment of patients with AD,UF and endometriosis is controversial and lacking clear evidence based algorithms. Despite their topical character, especially AD and DE (and UFs as well if present as multiple lesions) can be classified as systemic diseases in relation to women´s fertility. The presumed impact of these pathologies to endometrial receptivity (no matter they do not occur in the uterine cavity itself) can bes

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📋 Eligibility rules (as published)
Inclusion Criteria: * agreement with participation in the study * age between 18 - 45 years (at the start of patient´s participation in the study)women with at least 1 year infertility Exclusion Criteria: \-
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What it tests

  • cytoreductive resection of adenomyosis, myomectomy, resection of endometriosis
  • hysteroscopy
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Where

1 site
General Hospital in Prague
Prague, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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