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Evaluation of Maxillary Expansion Using Clear Aligners' Therapy in Patients With Cleft Lip and Palate at the Mixed Dentition Stage

RecruitingNAAges 6 Years - 12 YearsAllCairo University
NCT06994754 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the aligners can expand upper dental arch in patients with cleft lip and palate at age of 6-8 years old to correct their collapsid archs. The main questions it aims to answer are: Does aligners can achieve transverse dento-skeletal changes? Does aligners can achieve anteroposterior and vertical dento-skeletal changes? Participants will: Wear sequence of aligners (each for 10 days). Visit the clinic every month for checkups. 3D x-ray and intraoral scan will be taken after completion of the aligners set to evaluate the intervention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Mixed dentition. * Both males and females. * Bilateral cleft lip and palate. * Lip repair performed between 3 and 6 months of age and palate repair performed between 12and 24 months of age. * Presence of maxillary constriction that needs maxillary expansion. * Good periodontal health. * No previous orthodontic treatment. Exclusion Criteria: * Syndromic cleft lip and palate patients. * Taking medications that influence growth.
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What it tests

  • clear aligners
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Where

1 site
Faculty of Dentistry - Cairo University
Cairo, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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