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Combining Brain Stimulation and Physiotherapy for the Management of Chronic Low Back Pain

RecruitingNAAges 18 Years - 65 YearsAllLaval University
NCT06999772 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic low back pain (CLBP) is a major health challenge in Canada, leading to substantial disability and socioeconomic burden, particularly among Veterans. In military Veterans, LBP is the most common chronic pain condition. Conventional interventions have limited effectiveness. The refractoriness to interventions suggests that specific CLBP mechanisms may be missed by current treatments, prompting a shift towards psychologically informed approaches which aim to address emotional and cognitive factors alongside biomedical aspects. The integration of these concepts into physiotherapy is called psychologically informed physiotherapy (PiP). Despite promising results of PiP from randomized controlled trials, residual pain and disability often persist in Veterans. Non-invasive brain stimulation, such as repetitive transcranial magnetic stimulation (rTMS), may enhance the effectiveness of PiP

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults between 18 and 65 years old * Military Veterans with non-specific chronic low back pain (\> 3 months, \> 50% of the days in the last 6 months) * High level of psychosocial factors, scoring ≥4 on the Start Back Screening Tool * Functional limitations, scoring ≥ 15% on the Oswestry Disability Index (ODI) Exclusion Criteria: * Non-musculoskeletal conditions causing low back pain (e.g., neoplasia, fracture) * Diagnosis of drug or alcohol abuse * Change of drug dosage in the last month for the treatment of pain or mental health * Presenting with any specific rTMS-related exclusion criteria such as previous seizure/convulsion, cochlear implant, and pregnancy
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What it tests

  • Active rTMS
  • Sham rTMS
  • Psychologically-informed physiotherapy (PiP)
  • Usual physiotherapy
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Where

2 sites
Centre interdisciplinaire de recherche en réadaptation et intégration sociale (CIRRIS)
Québec, Canada
Cirris (Centre Interdisciplinaire de Recherche en Réadaptation et Intégration Sociale)
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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