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Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire de la Guadeloupe
NCT07001189 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Sickle cell disease is a chronic disease characterized by multiple vaso-occlusive complications. The basic treatment for patients with a vaso-occlusive crisis (VOC) is based on adequate hydration, oxygen therapy and pain control. Loco Regional Anesthesia (LRA) is one of the major treatments in resuscitation anesthesia for both anesthesia and analgesia. LRA allows effective and almost immediate pain control by blocking nerve afferents in a given area. LRA could decrease the inflammatory response during crises and accelerate resolution of the crisis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * patients adult \>18 years * patients with vaso-occlusive crisis Exclusion Criteria: * Pregnant or breastfeeding women * Blood transfusion within the last 3 months * Lack of affiliation with the French social security system * Protected individuals
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What it tests

  • Not listed
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Where

1 site
Chu de La Guadeloupe
Pointe-à-Pitre, Guadeloupe
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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