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Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease

RecruitingNAAges 6 Years - 18 YearsAllAcademisch Medisch Centrum - Universiteit van Ams…
NCT07001631 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Children with sickle cell disease may experience frequent painful episodes. This, together with the traumatic experiences during a hospitalization, can lead to the development of posttraumatic stress reactions. As the stress can trigger painful episodes (pain crisis) in children with sickle cell disease, the investigators think that treating these stress symptoms can reduce the pain-related problems in their lives. Eye Movement Desensitization and Reprocessing (EMDR) is proven to be an effective trauma treatment for posttraumatic stress disorder. Research studies show that EMDR can reduce pain in adults. The investigators want to study now if EMDR effective is in reducing pain-related problems in children with sickle cell disease.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Medical diagnosis of SCD * Age between 6 and 18 years old * Elevated pain interference scores: Reporting above the clinical cut-off T-score of 49 on PROMIS Pain Interference (parent-proxy version for children from 6-7 years and self-report version for children from 8 years). * Having sufficient knowledge of the Dutch or English languages to complete the assessments Exclusion Criteria: * Undergone successful stem cell transplantation * Pregnant adolescents * Current unsafety that is likely to interfere with psychological therapy for example ongoing domestic violence * Major interfering acute medical or psychiatric condition, such as psychosis, substance dependence, current severe self-harm or high risk for suicide requiring immediate treatment * Receiving psychological (trauma) treatment by another therapist at the same time * IQ estimated to be \< 80 based on information contained in the medical history or information from educational services/school
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What it tests

  • Eye Movement Desensitization and Reprocessing (EMDR)
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Where

1 site
Amsterdam UMC
Amsterdam, Netherlands
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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