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Correlation Study Between SMA Blood Flow Reactivity and Acute Gastrointestinal Injury in Critically Ill Patients

Recruitingn/aAges 18 Years - 80 YearsAllPeking Union Medical College Hospital
NCT07001943 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to address the challenges of enteral nutrition support in critically ill ICU patients with varying gastrointestinal function. We'll use bedside Doppler ultrasound to monitor superior mesenteric artery (SMA) blood flow changes post - feeding, exploring its correlation with Acute Gastrointestinal Injury (AGI) and other hemodynamic indicators. Our goals are to identify the patterns of SMA blood flow changes, establish a predictive model linking SMA blood flow reactivity to AGI risk, and propose individualized enteral nutrition strategies based on intestinal hemodynamics. Through this innovative approach, we hope to enhance the safety of enteral nutrition, reduce AGI incidence, and improve patient outcomes.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged ≥18 years and ≤80 years. * Admitted to the study with a expected stay of more than 72 hours. * Require initiation of enteral nutrition support. Exclusion Criteria: * Pre-existing severe gastrointestinal diseases. * Patients with gastrointestinal bleeding. * Patients with bowel obstruction. * Pregnant or lactating women. * Patients with contraindications to bedside Doppler ultrasound.
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What it tests

  • enteral nutrition
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Where

1 site
Peking union medical college hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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