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Timing of Coronary Angiography in NSTEMI Complicated by Acute HF

RecruitingNAAges 19 Years - anyAllChonnam National University Hospital
NCT07002164 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Study objectives: To determine the optimal timing of coronary angiography (CAG) in patients with non-ST-segment elevation myocardial infarction (NSTEMI) complicated by acute decompensated heart failure (AHF). The primary objective of this trial is to test the hypothesis that immediate CAG ≤2 hours after establishment of NSTEMI diagnosis would result in a significant reduction in primary composite outcome of death from any cause, non-fatal myocardial infarction (MI), or hospitalization for heart failure (HF) at 12 months after randomization as compared with delayed CAG after stabilization. Study hypothesis: Immediate CAG ≤2 hours after establishment of NSTEMI diagnosis would result in a significant reduction in primary composite outcome of death from any cause, non-fatal myocardial infarction (MI), or hospitalization for heart failure (HF) at 12 months after randomization as compared w

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age ≥19 years * Non-ST-segment elevation myocardial infarction * New-onset or worsening of dyspnea (New York Heart Association class ≥2) * Pulmonary congestion * Patient's or guardian's consent after understanding the study Exclusion Criteria: * Cardiogenic shock at initial presentation * ST-segment elevation myocardial infarction * ST-segment elevation ≥0.1 mV in at least 2 contiguous leads, or * New onset left bundle branch block * Posterior wall myocardial infarction * Refractory angina * Life threatening ventricular arrhythmias * Life expectancy \<1 year * Apparently non-ischemic cause of HF * Pregnancy and lactation * History of coronary artery bypass grafting (CABG), or planned CABG * Patient's refusal to participate in study
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What it tests

  • Immediate coronary angiography
  • Delayed coronary angiography
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Where

20 sites
Gyeongsang National University Changwon Hospital
Changwon, South Korea
Keimyung University Dongsan Hospital
Daegu, South Korea
Kyungpook National University Hospital
Daegu, South Korea
Yeongnam University Medical Center
Daegu, South Korea
Chungnam National University Hospital
Daejeon, South Korea
Chonnam National University Hospital
Gwangju, South Korea
Gwangju Veterans Hospital
Gwangju, South Korea
Kwangju Christian Hospital
Gwangju, South Korea

…and 12 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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