🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Diaphragmatic Function and Respiratory Drive in OSA and COPD

Recruitingn/aAges 18 Years - 80 YearsAllNanjing Medical University
NCT07003399 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This cross-sectional observational study aims to assess the diaphragmatic morphofunction and respiratory drive characteristics among patients with obstructive sleep apnea (OSA), chronic obstructive pulmonary disease (COPD), overlap syndrome (OS), and healthy controls. Using ultrasound imaging and surface diaphragm electromyography (EMGdi), the study will explore group differences in diaphragmatic morphology, function, and respiratory drive indicators, and evaluate their clinical significance in disease differentiation and severity assessment.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. Patients aged between 18 and 80 years. 2. For OSA Group: Diagnosed obstructive sleep apnea with AHI ≥ 5 events/hour based on overnight polysomnography. 3. For COPD Group: Diagnosed chronic obstructive pulmonary disease based on GOLD guidelines. 4. For Overlap Group: Diagnosed both OSA (AHI ≥ 5) and COPD. 5. For Control Group: Healthy volunteers with no known respiratory diseases or sleep disorders. 6. Ability and willingness to provide informed consent for participation in the study. Exclusion Criteria: 1. Severe cardiovascular diseases (e.g., unstable angina, heart failure NYHA III/IV). 2. Severe hepatic or renal insufficiency. 3. Neuromuscular diseases affecting respiratory muscles. 4. Recent upper airway or thoracic surgery (within 3 months). 5. Pregnancy or breastfeeding. 6. Participants who cannot complete assessments due to cognitive impairment or poor cooperation.
💊

What it tests

  • Diaphragmatic Ultrasound and EMG Assessment
📍

Where

1 site
The First Affiliated Hospital of Nanjing Medical University
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy