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Multi-modal Adverse Events Prediction for Premature Coronary Heart Disease Trial: MAP-CHD Trial

Recruitingn/aAges 18 Years - 45 YearsAllChina National Center for Cardiovascular Diseases
NCT07004452 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this observational cohort study is to establish a risk prediction model for adverse events in Chinese individuals under 45 years old with premature coronary artery disease. The main questions it aims to answer are: * What are the major risk factors for poor prognosis in Chinese patients with premature coronary artery disease? * What is the difference in the prognosis of patients with premature coronary heart disease with different phenotypes? Participants taking no mandatory intervention will be followed up for 2 year, with blood tests at 1 year and outpatient or telephone interviews at other timepoints.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18-45 years; * Clinically confirmed CAD with ≥50% luminal stenosis in at least one major coronary artery or significant branch, verified by coronary angiography; * For acute coronary syndrome (ACS) or percutaneous coronary intervention (PCI) patients: clinical stability meeting discharge criteria post-treatment; * Voluntary participation with signed informed consent. Exclusion Criteria: * Heart transplant recipients; * Severe systemic comorbidities with life expectancy \<1 year; * Previous enrollment in other drug/device clinical trials without completing the primary endpoint observation period; * Inability to comply with follow-up (e.g., dementia, severe psychiatric disorders).
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What it tests

  • Not listed
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Where

1 site
FuWai Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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