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Diagnostic Value of Confocal Laser Endomicroscopy (CelTouch) for Peripheral Lung Lesions

Recruitingn/aAges 18 Years - 80 YearsAllGuangzhou Medical University
NCT07004946 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study uses CelTouch to explore patients with lung lesions scheduled for lung biopsy. By comparing with preclinical CLE images and pathological images, CLE diagnostic criteria for benign and malignant lung lesions under the microscope will be established; the performance of CLE in diagnosing peripheral lung lesions will be validated through multicenter clinical research; and a CLE atlas for peripheral lung lesions will be constructed to establish a visual classification diagnostic system for peripheral lung lesions. (1) Comparative Study of In Vivo CLE Images and Pathological Images in the Diagnosis of Peripheral Lung Lesions 1. Collect CLE images and histopathological sections of clearly diagnosed peripheral lung lesions. 2. A diagnostic team composed of 1 bronchoscopy expert, 1 pathology expert, and 2 CLE experts will correlate in vivo and ex vivo CLE images of lung lesions with

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Aged ≥18 years, with lung lesions detected by chest CT and scheduled for lung biopsy; 2. Preoperative CT indicates the presence of a bronchus leading to the lesion to be biopsied; 3. Able to understand and willing to sign a written informed consent form. - Exclusion Criteria: 1. Those with contraindications to general anesthesia or bronchoscopy; 2. Patients with uncorrectable coagulation disorders; 3. Unable to discontinue therapeutic anticoagulants within an appropriate time interval before surgery; 4. Patients with severe liver or kidney dysfunction, cardiovascular and cerebrovascular diseases, mental illnesses, etc.; 5. Pregnant or lactating patients; 6. Those without a clear histological or clinical diagnosis; 7. Subjects deemed unsuitable by the investigator. -
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What it tests

  • Not listed
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Where

1 site
The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510163
Guangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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