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Effects Of Intra-Operative Intra-Articular Cocktail Injection In Patella Open Reduction And Internal Fixation

RecruitingPhase 4Ages 18 Years - anyAllThe University of Hong Kong
NCT07006168 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The objective of this study is to demonstrate the safety and efficacy of an intra-articular analgesics cocktail injection for post-operative patella fracture fixation patients, by comparing post-operative pain relief and functional recovery among study subjects who received the injection and those who did not receive the injection. Secondary objective is to demonstrate the health economic effects of intra-articular analgesics cocktail injection by reducing length of hospital stay and reducing bed-stay related complications.

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📋 Eligibility rules (as published)
Inclusion Criteria: * acute patella fracture requiring open reduction and internal fixation; * able to consent to surgery; * pre-morbid able to ambulate Exclusion Criteria: * open fracture; * polytrauma; * previous knee arthroplasty; * history of chronic pain, * insulin-dependent diabetes mellitus, or peptic ulcer disease; * chronic users of glucocorticoids, immunosuppressants, or immune-modulating agents, or of strong opioids (e.g.: morphine, fentanyl, hydromorphone, methadone, oxycodone, or meperidine); * hepatitis B or C carrier; * renal impairment (creatinine \[Cr\], \>200 mmol/L)
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What it tests

  • Ketorolac 15mg
  • Triamcinolone Acetonide 40mg
  • Ropivacaine HCL 1% 15ml
  • 0.9 % Normal Saline 35ml
  • Adrenaline 1:1000 0.5ml
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Where

1 site
Queen Mary Hospital, The University of Hong Kong
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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