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Phospholipid-rich Dairy Extract for Cognitive Function

RecruitingNAAges 55 Years - 85 YearsAllPusan National University Yangsan Hospital
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to determine whether dietary phospholipid-rich dairy milk extract improves cognitive function in adults with mild cognitive impairment and to assess its safety. The main questions are: * Does dietary phospholipid-rich dairy milk extract improve cognitive function in participants? * What side effects occur when participants take phospholipid-rich dairy milk extract?

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age: Adults aged 55-85 years (inclusive), both male and female * Global Deterioration Scale (GDS) score of 2-3: GDS 2: Subjective memory impairment without objective evidence GDS 3: Mild objective memory impairment * Absence of dementia according to established diagnostic criteria * Ability to read Korean Exclusion Criteria: * Severe medical conditions within the past 6 months: History of severe cerebrovascular disease (cerebral infarction, cerebral hemorrhage), cardiac disease (angina, myocardial infarction, heart failure, arrhythmia requiring treatment), or malignancy (Note: Participants with a history of cerebrovascular or cardiac disease who are clinically stable may be included at the investigator's discretion) * Cognitive impairment-associated diseases: Dementia, Parkinson's disease, cerebral infarction, or other conditions associated with cognitive decline Uncontrolled hypertension: Blood pressure โ‰ฅ160/100 mmHg (measured after 10 minutes of rest) * Poor glycemic control: Fasting blood glucose โ‰ฅ160 mg/dL in diabetic patients * Uncontrolled thyroid dysfunction: Currently receiving treatment for uncontrolled hypothyroidism or hyperthyroidism * Renal impairment: Serum creatinine โ‰ฅ2 times the upper limit of normal for the institution * Hepatic impairment: AST or ALT โ‰ฅ2 times the upper limit of normal for the institution * Severe gastrointestinal symptoms: Complaints of severe heartburn, dyspepsia, or other gastrointestinal distress * Medications affecting cognitive function within the past month: Use of drugs (antipsychotics, anti-degenerative agents, cognitive enhancers, tricyclic antidepressants, hormone replacement therapy) or health functional foods that may influence cognitive function due to dementia or other cognitive abnormalities * Other clinical trial participation: Participation in other drug clinical trials within the past month or planned participation during the study period * Alcohol abuse * Food allergies: Known allergic reactions to study product components * Investigator discretion: Any other condition deemed inappropriate for study participation by the investigator
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What it tests

  • Phospholipid-rich dairy milk extract
  • Placebo
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Where

1 site
Pusan National University Yangsan Hospital
Yangsan, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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