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Characterising the Neuromuscular Function of Post Stroke Patients

Recruitingn/aAges 40 Years - 85 YearsAllUniversity of Nottingham
NCT07013188 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Strokes are a leading cause of death and disability in developed countries, with significant economic and social impacts. Defined by the WHO, strokes cause rapid and lasting disturbances in cerebral function. In the UK, strokes occur every five minutes, affecting 100,000 people annually and resulting in substantial physical impairments and financial costs. Although stroke-related deaths have decreased due to improved treatments and awareness, strokes remain a major cause of death and disability worldwide, especially in lower-income countries. Strokes typically cause unilateral deficits, leading to significant daily challenges and necessitating tailored rehabilitation strategies such as CIMT, FES, and VR Rehab. As the population ages, innovative neurorehabilitation approaches are essential to enhance functional recovery post-stroke. This pilot study aims to better understand the neuromusc

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Aged between 40-85 years * Willing and able to give informed consent for participation in the study * Had a confirmed stroke within the last 5 years * Self-reports persisting post-stroke loss of unilateral limb function Exclusion Criteria: * • Diagnosis of cognitive impairment/dementia * Current or recent (\<2y) malignancy * Severe respiratory disease (e.g., uncontrolled asthma, COPD, pulmonary hypertension) * Active cardiovascular disease: Uncontrolled hypertension (BP\>160/100mmHg); Recent (\<12mo) cardiac event; Heart failure (Class III/IV); Significant arrhythmia; Unstable angina * Metabolic disease: Untreated hyper/hypoparathyroidism; Cushing's disease * Significant musculoskeletal disorders (based on clinical opinion) * Dialysis patients * Recent steroid treatment within 6 months or hormone replacement therapy * Mobility dependant (wheelchair dependency)
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What it tests

  • Neuromuscular function
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Where

1 site
Royal Derby Hospital branch, School of Medicine, University of Nottingham
Derby, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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