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Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure

Recruitingn/aAges 18 Years - anyAllSemmelweis University
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In plain words

What the trial is, and whether it could suit you

The clinical and demographic characteristics of patients undergoing transcatheter aortic valve implantation (TAVI) pose unique challenges for coronary computed tomography (CT) imaging, as this patient population is mainly composed of elderly, frail individuals with severe aortic stenosis, multiple comorbidities, high prevalence of heavily calcified coronary artery disease (CAD) and revascularized coronary arteries. Such vulnerable patients could benefit from a more precise assessment and characterization of their CAD with ultra-high resolution (UHR) photon-counting detector (PCD) CT that would potentially avoid the need for pre-implantation invasive coronary angiography (ICA). This international multicenter prospective registry study aims to investigate the feasibility and diagnostic accuracy of PCD-CT in the assessment of CAD in the high-risk population of patients undergoing TAVI, as c

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📋 Eligibility rules (as published)
Inclusion Criteria: * Clinically indicated TAVI * Clinically indicated CT and invasive coronary angiography * There are no contraindications to CT angiography. * Understanding and signing the consent form Exclusion Criteria: * Pregnancy or breastfeeding * Chronic renal failure (eGFR \<30 ml/m2) * Active oncological treatment * Any condition for which TAVI is contraindicated and therefore no prior radiological investigation of TAVI is indicated
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What it tests

  • Ultra-High Resolution Photon Counting Detector Coronary Computed Tomography Angiography
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Where

7 sites
Medical University of South Carolina
Charleston, United States
Albert-Ludwigs-Universität Freiburg
Freiburg im Breisgau, Germany
University Medical Center Mainz
Mainz, Germany
Universitätsklinikum Tübingen
Tübingen, Germany
Semmelweis University
Budapest, Hungary
Maastricht University
Maastricht, Netherlands
University Hospital of Zürich
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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