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SSGJ-705 Monotherapy and Combination Therapy in Advanced HER2-Expressing Solid Tumors

RecruitingPhase 2Ages 18 Years - 75 YearsAllShenyang Sunshine Pharmaceutical Co., LTD.
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In plain words

What the trial is, and whether it could suit you

This study was an open-label phase Ⅱ study to evaluate the safety and efficacy of SSGJ-705 Monotherapy and Combination Therapy in patients with advanced HER2-Expressing Solid Tumors.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Males and/or females over age 18. * Histologically and/or cytologically documented local advanced or metastatic non-Small Cell Lung Cancer(NSCLC),Breast Cancer(BC)or Gastric/Gastroesophageal Junction Cancer (G/GEJC). * Eastern Cooperative Oncology Group (ECOG) performance status of 0-1. * Expected survival \>3 months. * Signed informed consent form. Exclusion Criteria: * Any remaining adverse events (AEs) \> grade 1 from prior anti-tumor treatment as per Common Terminology Criteria for Adverse Events(CTCAE) v5. 0, with exception of hair loss, fatigue, and grade 2 peripheral neurotoxicity. * Pregnant or nursing women or women/men who are ready to give birth. * symptomatic central nervous system metastasis. * Allergy to other antibody drugs or any excipients in the study drugs. * Inadequate organ or bone marrow function.
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What it tests

  • SSGJ-705
  • PD-1/L1 inhibitor combined with chemotherapy
  • SSGJ-705 combined with chemotherapy
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Where

1 site
Zhejiang Cancer Hospital
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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