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Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital

Recruitingn/aAges 13 Years - 80 YearsAllSohag University
NCT07022236 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis. The prevalence of thyroid dysfunction in dialysis patients has been reported to range from 20% to 60%, highlighting the need for routine screening and management in this vulnerable group (Kuo et al., 2024). Thyroid hormones play a crucial role in regulating various physiological processes, and their dysregulation can lead to complications such as cardiovascular disease, anemia, and impaired quality of life, which are particularly concerning in the dialysis population (Smith et al., 2024). The relationship between CKD and thyroid dysfunction is complex and multifactorial. Uremic toxins can interfere with the hypothalamic-pituitary-thyroid axis, leading to alterations in thyroid hormone production and metabolism.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years and older. * Patients diagnosed with end-stage renal disease (ESRD) on regular hemodialysis for at least 3 months. Exclusion Criteria: * Known Thyroid Disorders: Patients with a history of thyroid disease (e.g., hypothyroidism, hyperthyroidism) prior to starting dialysis. * Recent Thyroid Treatment: Patients who have received treatment for thyroid dysfunction (e.g., thyroid hormone replacement, antithyroid medications) within the last six months. * Patients with acute kidney injury (AKI) or those who are not on regular dialysis. * Pregnant or lactating women. * Patients with systemic illnesses or medications that could interfere with thyroid function tests (e.g., corticosteroids, lithium).
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What it tests

  • Thyroid profile
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Where

1 site
Hospital
Sohag, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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