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โ† Trials
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The Link Between Physical Activity and Brain Health in Healthy Adults

Recruitingn/aAges 40 Years - 75 YearsAllTechnical University of Madrid
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In plain words

What the trial is, and whether it could suit you

The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is: Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days/week of moderate-vigorous intensity). * Group B: sedentary individuals, (i.e., perform \<150 min of moderate intensity exercise per week or IPAQ score\<600 MET min/week). * In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations. * Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition Exclusion Criteria: * Medical conditions that have a high risk of associated cognitive symptoms. * Severe head injury with loss of consciousness within the previous 5 years. * Alcoholism (\>3 alcoholic drinks per day). * Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics. * Hearing or visual impairment that would preclude testing * History of neurological disease with clinically relevant impact on cognition (e.g. cerebrovascular disease). * Incidental structural brain findings with impact on cognitive impairment or survival (e.g., malignant brain tumor). * Presence of severe systemic disease (e.g., cancer under treatment). * Consumption of anabolic substances. * Problems understanding spoken or written Spanish. * Those with pacemakers or metallic implants that may interfere with the MRI.
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What it tests

  • Not listed
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Where

1 site
Faculty of Physical Activity and Sports Sciences (INEF)
Madrid, Spain
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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