AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Clinical Application Study of PET/CT for Differential Diagnosis of Non-small Cell Lung Cancer

RecruitingNAAges 18 Years - 80 YearsAllRenJi Hospital
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study aims to explore the efficacy of Trop2, EpCAM-specific PET/CT imaging for noninvasive visualization of Trop2 or EpCAM expression levels in non-small cell lung cancer; and to explore the differences between novel target-specific PET/CT examinations and conventional 18F-FDG PET/CT in the diagnosis and differential diagnosis of solid lung nodules.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age 18-80 years; 2. Imaging studies suspecting non-small cell lung cancer; 3. Solid lung nodules (โ‰ฅ8 mm in diameter) diagnosed by chest ct, which are subject to 18F-FDG PET/CT and surgical resection/biopsy of lung nodules according to the NCCN guideline specifications for NSCLC in the 2024 edition; 4. Patients or family members agreed to participate in this clinical study and signed an informed consent form. Exclusion Criteria: 1. Women during pregnancy and lactation; 2. Persons with a history of surgery and trauma that significantly affects metabolic distribution and anatomical structure; 3. Persons with severe other systemic diseases or known hypersensitivity to humanized monoclonal antibody products; 4. Patient is unable to cooperate in completing the PET/CT examination; 5. Patient has participated in other clinical studies within the past year that have resulted in radiation exposures in excess of an effective dose of 50 mSv, in addition to the radiation exposures anticipated from participation in this clinical study; 6. Patient should not participate in this clinical trial in the opinion of the investigator.
๐Ÿ’Š

What it tests

  • [68Ga]Ga-NOTA-T4
  • [68Ga]Ga-NOTA-RT4
  • [18F]F-RESCA-T4
  • [18F]F-RESCA-RT4
  • [18F]F-RESCA-EPCD6
๐Ÿ“

Where

1 site
Renji Hospital, School of Medicine, Shanghai Jiao Tong University
Shanghai, China
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy