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Women With isoLated acUte cyStitis and Macroscopic Hematuria. Is Further Investigation Needed?

Recruitingn/aAges 18 Years - 110 YearsFemaleVastra Gotaland Region
NCT07037589 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective multicenter observational study evaluates whether women ≥50 years with isolated acute hemorrhagic cystitis (AHC) and macroscopic hematuria require full malignancy workup. All participants undergo standard diagnostics (cystoscopy, CT urography, cytology), with 12-month follow-up for cancer detection. The aim is to identify low-risk patients where invasive investigations may be safely avoided.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Women ≥50 years of age. 2. Macroscopic hematuria. 3. Presenting for evaluation within the SCP for macroscopic hematuria. 4. Ability to provide informed consent. Exclusion Criteria: 1. Prior diagnosis of bladder cancer, renal cancer, or upper tract urothelial carcinoma (UTUC). 2. Cognitive impairment preventing informed consent. 3. Ongoing or recent treatment for urological malignancy. 4. Serious comorbidities affecting participation or safety. 5. Pregnant women.
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What it tests

  • investigation setting (cystoscopy + CTU + cytology)
  • Cystoscopy - CTU - cytology (if needed)
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Where

1 site
Uddevalla Hospital
Uddevalla, Sweden
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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