๐ฌIn plain words
What the trial is, and whether it could suit you
This study aims to evaluate the effectiveness of a multimodal intervention using immersive virtual reality (Virtual-METS) to improve cognitive function in middle-aged adults with metabolic syndrome and subjective cognitive complaints. The intervention combines cognitive training and physical exercise in group sessions over 12 weeks.
Sign in to get the eligibility rules as simple questions to take to your doctor.
๐ Eligibility rules (as published)
Inclusion Criteria:
* Demonstrated criteria for the MetS: central obesity (waist circumference โฅ 94 cm for men or โฅ 80 cm for women) and at least 2 of the criteria described as follow: Triglycerides โฅ 150 mg/dl or specific treatment of this lipid disorder; HDL-C \< 40 mg/dl (men) or \< 50 mg/dl (women) or specific treatment of this lipid disorder; Systolic blood pressure โฅ 130 mmHg or diastolic blood pressure โฅ 85 mmHg or previously diagnosed hypertension treatment; Basal glycemia โฅ 100 mg/dl or type 2 diabetes previously diagnosed).
* Age: between 45 and 70 years old.
* Subjective cognitive complaints: Subjective Cognitive Decline Questionnaire (โฅ 7).
* Ability to fully understand and speak Spanish or Catalan.
Exclusion Criteria:
* Confirmed or suspicion of dementia (MMSE\<24).
* Diagnosis of severe psychiatric, neurological, developmental disorders, systemic pathologies, hematological, hormonal, nutritional pathology, and/or neoplasm that are known to cause cognitive deficits.
* Other severe comorbidities considered a probable bias for the study: a cardiac history of unstable angina, recent myocardial infarction within the last 3 months, congestive heart failure, significant heart valve dysfunction, or unstable hypertension; taking medications that could negatively affect cognitive function.
* Physical, motor, or sensory alterations that impede the neuropsychological examination or the rehabilitation program.