🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

No Reduction Compared to Closed Reduction for Distal Radius Fractures in Patients Over 65 or Older

RecruitingNAAges 65 Years - anyAllTampere University Hospital
NCT07042139 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

DISCLOSE trial is a randomized controlled trial including 532 participants with low-energy distal radius fractures. The primary objective is to evaluate whether casting without prior closed reduction is equivalent to casting following closed reduction with respect to wrist-related pain and disability, as measured by the Patient-Rated Wrist Evaluation (PRWE) score at 12 months, in patients aged 65 years or older with a displaced distal radius fracture. * Primary endpoint will be PRWE at 12 months * Follow-up visits are scheduled at 3 and 12 months. 5-year follow-up will be considered as an exploratory endpoint

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Age 65 years or older * Independent living patients * Displaced distal radius fracture (AO/OTA 23A/23C) with 15-40 degree dorsal angulation, and/or of shortening of the radius for more than 2 mm. * Associated ulnar styloid fracture is permitted * Low energy injury, (fall from \<1 m) Exclusion Criteria: * Patient unable to provide consent * Patients who are actively working in a paid position * Volar angulation, partial articular fractures (AO/OTA 23B) * Concomitant fracture of the ulna proximal to the base of the styloid process * Associated fracture or dislocation in any other body part that would affect the use of the injured distal radius * Distal radius fractures in both arms * Open injury, Gustilo 2 or higher * No bony contact between the main fragments * High energy injuries
💊

What it tests

  • No reduction
  • Closed Reduction
  • Casting
📍

Where

10 sites
Viborg regional Hospital
Viborg, Denmark
Tartu University Hospital
Tartu, Estonia
Tampere University Hospital
Tampere, Finland
Helsinki University Hospital
Helsinki, Finland
Kanta-Häme Central Hospital
Hämeenlinna, Finland
Kuopio University Hospital
Kuopio, Finland
Oulu University Hospital
Oulu, Finland
Pori Central Hospital
Pori, Finland

…and 2 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy