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Efficacy and Mechanisms of Virtual Reality Treatment of Phantom Leg Pain.Home-Based Treatment

RecruitingNAAges 18 Years - 100 YearsAllAlbert Einstein Healthcare Network
NCT07044323 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

After amputation of an arm or leg, up to 90% of subjects experience a "phantom limb", a phenomenon characterized by persistent feelings of the missing limb. Many subjects with a phantom limb experience intense pain in the missing extremity that is often poorly responsive to medications or other interventions. The study will explore the feasibility and efficacy of a home-based, active VR treatment for phantom limb pain (PLP).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age 18 -100 * Capacity to provide Informed Consent * Unilateral above or below knee amputation more than 3 months prior to enrollment * Absence of cognitive impairment, operationally defined as a Montreal Cognitive Assessment score of 18 or greater1. * Pain averaged over the preceding 1 month in the phantom limb rated as greater than 4 on a scale of 0-10. Exclusion Criteria: * History of significant medical or neurological disorder such as stroke or moderate to severe traumatic brain injury (operationally defined as loss of consciousness for more than 30 minutes) * History of significant or poorly controlled psychiatric disorders * Substantial depression or anxiety affecting their ability to perform tasks necessary for the study. * Current abuse of alcohol or drugs, prescription or otherwise * Nursing a child, pregnant, or intent to become pregnant during the study
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What it tests

  • Active Virtual Reality Treatment
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Where

3 sites
Jefferson Moss Rehabilitation Research Institute
Philadelphia, United States
University of Pennsylvania
Philadelphia, United States
University of Washington
Seattle, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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