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Biannual Review of Exhaled Air and Trends in Health Evaluation in COPD

RecruitingNAAges 40 Years - anyAllUniversitair Ziekenhuis Brussel
NCT07045948 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate how airway inflammation, lung function, and symptoms change over time in people with chronic obstructive pulmonary disease (COPD). Airway inflammation will be assessed using a simple breath test (FeNO) and a small blood sample to measure eosinophils, a type of white blood cell. Participants will be followed for one year, with three study visits (at the start, 6 months, and 12 months). The goal is to understand how these markers evolve and whether they differ between people who experience a worsening of symptoms (called exacerbations) and those who remain stable. All tests except for a small extra blood draw are part of routine COPD care. Participation does not affect standard treatment.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged ≥ 40 years * Diagnosed with COPD according to GOLD criteria * Attending routine follow-up visits every 6 months * Ability to provide informed consent Exclusion Criteria: * Recent respiratory tract infection or exacerbation (either moderate or se-vere) (\<4 weeks before inclusion) * Dominant asthmatic phenotype (ACO with asthma predominance) * Severe comorbidities interfering with participation or follow-up
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What it tests

  • Blood eosinophil Count
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Where

1 site
Universitair Ziekenhuis Brussel
Jette, Belgium
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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