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Remimazolam and Emergence Delirium in Pediatrics

RecruitingPhase 4Ages 1 Year - 6 YearsAllPeking University First Hospital
NCT07046364 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Emergence delirium is a common complication in pediatrics undergoing neurosurgery. Previous study showed that a single bolus of remimazolam was associated with lower incidence of postoperative agitation. Present study was designed to investigate if remimazolam supplemented to sevoflurane anesthesia could decrease the risk of emergence delirium in pediatrics undergoing neurosurgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Aged 1 to 6 years old * Planned to receive elective neurosurgery under general anesthesia * Expected duration of surgery \> 1 hour Exclusion Criteria: * Allergy to benzodiazepine * Use of other sedatives within 12 hours before surgery such as benzodiazepines, propofol, chloral hydrate, etc., * ASA classification IV or above * Unable to complete emergence delirium assessment, such as language, hearing or vision impairment.
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What it tests

  • Remimazolam
  • Normal Saline
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Where

2 sites
Peking University First Hospital
Beijing, China
Peking University First Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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