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Chitosan Irrigation in Premolar Root Canal Therapy (Randomized Trial)

RecruitingNAAges 18 Years - anyAllESRA DAฤžCI
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn which of three common root-canal rinsing (irrigation) methods removes bacteria most effectively in adult patients who need root-canal treatment. The main questions it will answer are: How much does a chitosan solution used alone lower the number of bacteria inside the root canal? Do the combinations sodium hypochlorite + chitosan or sodium hypochlorite + EDTA lower bacteria even more than chitosan alone? Researchers will compare the three irrigation methods to see which one achieves the greatest bacterial reduction. What participants will do Be randomly assigned to one of three groups: Group 1: Chitosan only Group 2: Sodium hypochlorite followed by chitosan Group 3: Sodium hypochlorite followed by EDTA Attend two clinic visits: Visit 1: Receive standard root-canal treatment under local anesthesia. Provide tiny paper-point samples from in

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients who agreed to participate in the study * Systemically healthy patient * Mandibular premolar teeth * Teeth that respond negatively to thermal tests and EPT * Patients who have not used antibiotics for at least 2 weeks Exclusion Criteria: * Teeth with previous primary root-canal treatment * Pregnant patients * Severely curved roots (\>25ยฐ curvature) * Canals with instrument separation during preparation * Calcified (obliterated) canals
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What it tests

  • Chitosan Low Molecular Weight (20-200 Mpa.S)
  • Sodium Hypochlorite
  • EDTA chelating agents
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Where

1 site
Ordu University
Ordu, Turkey (Tรผrkiye)
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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