AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Head-to-Head Comparison of Five Enhanced Depth of Focus IOLs and One Monofocal IOL

RecruitingNAAges 22 Years - 85 YearsAllAugenklinik Ahaus G + H GmbH & Co. KG
💬

In plain words

What the trial is, and whether it could suit you

Study Goal The goal of this clinical trial is to compare how well four different types of artificial lenses (called intraocular lenses or IOLs) help people see after cataract surgery. The main questions it aims to answer are: Which lens gives the best vision at different distances (far, middle, and close)? How satisfied are patients with their vision after surgery? How often do patients still need glasses after surgery? Who Can Participate Adults aged 22 to 85 years who need cataract surgery in both eyes and meet specific health requirements. Study Design Researchers compared six different lens types: TECNIS Eyhance - designed to improve middle-distance vision AcrySof IQ Vivity - extends the range of clear vision LuxSmart - uses special optics for better depth of focus Rayner EMV - uses gradual light-bending technology for smooth vision transition Eycryl SERT - modifies light focus

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Bilateral implantation of the same intraocular lens (IOL) model * Expected postoperative best-corrected distance visual acuity (BCDVA) of 0.8 (decimal) or better * Regular corneal astigmatism less than 1 diopter Exclusion Criteria: * Endothelial cell density \< 2,000 cells/mm² * Required IOL power for emmetropia falls outside the available range of +10.0 D to +30.0 D * Pupillary abnormalities * Intraocular inflammation * Recent ocular trauma or ocular surgery that is unresolved/unstable, or which may impair visual outcomes or increase patient risk * History of corneal refractive surgery (e.g., LASIK, LASEK, PRK) * Irregular astigmatism, as well as corneal abnormalities or opacities * Conditions associated with an increased risk of zonular rupture, including capsular or zonular anomalies that may lead to IOL decentration or tilt, such as pseudoexfoliation syndrome, trauma, Marfan syndrome, among others * Systemic or ocular diseases, or medications, that may impair vision, increase surgical risk, or confound study outcomes * Clinically significant dry eye disease affecting visual function * Anticipated need for retinal laser treatment or any other ocular surgical intervention during the study period * Pregnancy, planned pregnancy, breastfeeding, or any condition associated with hormonal fluctuations that may induce refractive changes * Continuous contact lens wear within the past 4 weeks * Inability to understand and/or complete study questionnaires * Advanced glaucoma with visual field defects * Age-related macular degeneration (exudative or geographic form)
💊

What it tests

  • Bilateral implantation of CT ASPHINA 409M
  • Bilateral implantation of TECNIS Eyhance ICB00
  • Bilateral implantation of AcrySof® IQ Vivity®
  • Bilateral implantation of LuxSmart™
  • Bilateral implantation of Eyecryl SERT
📍

Where

1 site
Augenklinik Ahaus
Ahaus, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy