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One-Stop manaGemEnT For A Swift Initiation of Endovascular Therapy

RecruitingNAAges 18 Years - anyAllProf. Dr. Jan Liman
NCT07052045 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Stroke, especially acute ischemic stroke (AIS) caused by a blocked blood vessel in the brain, is a leading cause of death and long-term disability. When the blockage is in a large blood vessel, a procedure called endovascular therapy (EVT)-where the clot is removed using a catheter-is highly effective. However, the sooner EVT is done, the better the outcome for the patient. Research has shown that delays between arriving at the hospital and starting EVT (called door-to-groin time) significantly reduce the chances of recovery. For example, reducing this time by just 15 minutes can mean 20 more patients (out of 1,000 treated) going home instead of to a care facility. Even a 10-minute improvement can result in over 100 extra days of independent living for patients and save more than $10,000 in healthcare costs per patient. To reduce these delays, hospitals have improved stroke workflows.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Symptoms suggestive of an acute ischemic stroke caused by a large or medium vessel occlusion as defined by a National Institute of Health Stroke Scale (NIHSS) Score of ≥ 10 points * Patient presents directly to the treating hospital (mothership patient) within 4.5 hours of last seen well (LSW) * Age ≥ 18 years * Patient was independent in daily activities prior to the stroke (pre stroke modified Rankin Scale of 0 - 2) * Endovascular treatment team available (Neurologist, Interventionist, Anesthesiologist, Nursery, Technicians) * Informed Consent as documented by signature or fulfilling the criteria for emergency consent procedures Exclusion Criteria: * Severe comorbidities, which will likely prevent improvement or follow-up * In-hospital stroke * Clinical symptoms suggestive of intracranial hemorrhage (deterioration of patient during transport, vomiting or depressed consciousness) * Strong suspicion of functional neurological symptom disorder / conversion disorder * Hemodynamically unstable patients who require advanced vital support * Angiography room occupied by other procedure
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What it tests

  • One Stop Management
  • Usual care management
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Where

2 sites
Klinik für Neurologie, Universitätsklinik der Paracelsus
Nuremberg, Germany
University Hospital Basel
Basel, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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