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Investigation of a New Window Into Intracranial Pressure: Venous Occlusion Pressure of the Isolated Periorbital Vein

RecruitingNAAges 18 Years - 95 YearsAllUniversity of Freiburg
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In plain words

What the trial is, and whether it could suit you

Elevated intracranial pressure (ICP) occurs when pressure inside the skull rises above normal levels, potentially leading to brain damage or herniation. Monitoring ICP is critical for managing conditions like brain tumors, traumatic brain injury, and stroke. Current ICP monitoring methods are invasive and carry risks, including infection and brain damage. For less severe cases, lumbar puncture is a safer, less invasive alternative. This study explores the potential of a non-invasive method, using venous pressure near the eye, to estimate ICP. The goal is to assess whether the results from this non-invasive approach are similar to the invasive lumbar CSF pressure measurements.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: * Medical indication to perform routine craniospinal CSF dynamic testing according to standard operative procedures * Aged 18-95 * Willing and able to provide valid signed informed consent Exclusion Criteria: * Patients with any known ongoing, or history of, abnormal CSF communication * Patients with any kind of prior intervention for CSF diversion * Patients with acute brain damage within the preceding 6 months * Patients with transdural surgery within the preceding 6 months * Head wounds or hematoma that could hinder access to measurement site * Any known pathological condition linked to the orbital socket influencing venous outflow
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What it tests

  • venous occlusion pressure Measurement
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Where

1 site
Klinik für Neurochirurgie, Universitätsklinikum Freiburg
Freiburg im Breisgau, Germany
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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