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Assessment of Serum Catestatin Level in Acne Vulgaris Patients

RecruitingNAAges 18 Years - 40 YearsAllAswan University
NCT07054398 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Acne vulgaris is a persistent inflammatory condition of the pilosebaceous unit, affecting 85% of people between the ages of 12 and 24, it is regarded as one of the most common diseases in teenagers and young adults. Catestatin, a peptide derived from chromogranin A (CgA), was first discovered in 1997 as an acute nicotinic-cholinergic antagonist. Later, it was determined that CST is a pleiotropic hormone.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Healthy persons of both sexes with moderate and severe acne. Exclusion Criteria: * Pregnant and lactating women. * Immunocompromised patients. * Severe anemia. * History of chronic liver disease. * Hyperlipidemia * Non-inflammatory acne conditions. * History of neurologic disorders. * History of neoplastic disorders. * History of cardiac disease. * History of systemic acne treatment for at least 4 weeks prior to inclusion and no topical treatments for at least 2 weeks. * Cases with known hypersensitivity reaction to isotretinoin.
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What it tests

  • Isotretinoin
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Where

1 site
Aswan Unuversity Hospital
Aswฤn, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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