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Comparison of Pruritus Incidence After Intrathecal Morphine 0.1 vs 0.2 mg in Cesarean Section

RecruitingPhase 4Ages 18 Years - 45 YearsFemaleKhon Kaen University
NCT07054775 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study compares the incidence of pruritus (itching) requiring treatment between two doses of intrathecal morphine (0.1 mg vs 0.2 mg) when used for spinal anesthesia during cesarean section. The study aims to determine if the lower dose (0.1 mg) can reduce pruritus incidence while maintaining adequate pain relief.

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📋 Eligibility rules (as published)
Inclusion Criteria: • Pregnant women aged 18-45 years * Full-term pregnancy * Scheduled for non-emergency cesarean section * ASA physical status I-III * Non-complicated pregnancy Exclusion Criteria: * Contraindication to spinal anesthesia or study drugs * Refusal to participate in the study * BMI ≥ 40 kg/m² * History of systemic skin disease or current itchy skin condition * Use of antihistamines or anti-pruritic medications within 3 days prior to surgery
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What it tests

  • Morphine Sulfate
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Where

2 sites
Faculty of Medicine, Khon Kaen University
Khon Kaen, Thailand
Thepakorn Sathitkarnmanee
Khon Kaen, Thailand
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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