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Cognitive Remediation Method Using Rhythmic, Vocal and Corporal Musical Learning for Schizophrenia

RecruitingNAAges 18 Years - 60 YearsAllUniversity Hospital, Toulouse
NCT07055204 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Schizophrenia, affecting 1% of the population, is a persistent disorder characterized by varied symptoms. Antipsychotic medications effectively address positive symptoms (delusions, hallucinations) and relapse but have limited impact on negative symptoms (e.g., blunted affect, anhedonia) and cognitive impairment. These dimensions significantly influence social functioning and quality of life. Combining non-pharmacological approaches like Cognitive Remediation (CR) and psychosocial rehabilitation alongside antipsychotic drugs is recommended to enhance overall functioning and quality of life. Current CR programs show moderate effectiveness due to patient commitment issues. However, completed programs demonstrate higher efficacy. Real-life applicability of these programs lacks sufficient data. We propose musical learning for cognitive remediation due to its established cognitive benefits in

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patient with a diagnosis of schizophrenia or schizoaffective disorder (DSM-5 TR criteria) * Clinically stable (no full-time hospitalization related to schizophrenia for 3 months) * Regular psychiatric follow-up * Enrolled in at least 1 therapeutic or social out-of-home activity * No change in the antipsychotic treatment for 3 months (medication and/or dosage) * Have given free, informed and written consent to participate in the study. * Patient affiliated or beneficiary of a social security scheme Exclusion Criteria: * Patient with moderate to severe intellectual disability (clinical criteria) * Engaged in a Social rythmic or musical activity * Presenting an addictive comorbidity (excluding tobacco addiction and behavioural addictions) * Presenting a neurological pathology with cognitive impact * Involved in a neurocognitive remediation program
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What it tests

  • "Diapason & Metronome" musical learning
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Where

6 sites
CH de la Côte Basque
Bayonne, France
CH Le Vinatier
Bron, France
Assistance Publique Hôpitaux de Marseille
Marseille, France
Association route nouvelle
Toulouse, France
Centre de Santé MGEN
Toulouse, France
CH Gérard Marchant
Toulouse, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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