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Prevention of Desaturations Using Positive Airway Pressure or Capnometry During ERCP

RecruitingNAAges 18 Years - 99 YearsAllKarl Landsteiner University of Health Sciences
NCT07056075 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Although sedation during endoscopy is sufficiently safe, desaturations are among the most common side effects of endoscopic retrograde cholangiopancreatography (ERCP) procedures, occurring in approximately 20-30% of cases. Sedation during endoscopy increases the complication rate, and a significant proportion of severe and serious side effects are respiratory/airway-related. However, most patients require sedation to complete the procedure and achieve adequate outcomes during therapeutic ERCP. Therefore, improved measures to increase ERCP safety are needed. Since the demand for anesthesia in many centers already (far) exceeds current capacities, performing additional ERCPs under general anesthesia is not an option. Innovative ways to improve cardiorespiratory monitoring or respiratory management during ERCP could offer a solution without significantly increasing costs. Fortunately, dedic

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📋 Eligibility rules (as published)
Inclusion Criteria: * undergoing an interventional (intent) ERCP procedure * 18-99 years * Male or female * Nurse-administered sedation Exclusion Criteria: * History of allergic reaction to Propofol * Tracheostomy * Procedure requiring intubation, general anesthesia, or anesthesiologist backup (acute exacerbation of obstructive lung disease, acute congestive heart failure, supra-glottic or sub-glottic tumor, septic shock, e.g.) according to the endoscopist in charge * Pregnant patients
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What it tests

  • Nasal PAP Ventilation System
  • Low Flow Oxygen
  • Capnometry
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Where

2 sites
Division of Gastroenterology and Hepatology, Department of Medicine, Medical University Graz
Graz, Austria
Department of Internal Medicine 2, University Hospital of St Pölten
Sankt Pölten, Austria
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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