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Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis

RecruitingNAAges 16 Years - 30 YearsAllNova Scotia Health Authority
NCT07056894 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in significant challenges for individuals and their families, including difficulties with thinking, relationships, and overall well-being. They also carry significant economic costs, both for health care and lost productivity. Early intervention services have been shown to improve outcomes when provided during the first few years of illness known as early phase psychosis (EPP). However, substance use, especially alcohol and cannabis, can interfere with the effectiveness of these services. Many young people with psychosis misuse these substances, which can harm brain development, worsen symptoms, reduce medication use, and lower quality of life. Despite understandin

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📋 Eligibility rules (as published)
Inclusion Criteria: * This study will enroll individuals 16-30 years of age from the Early Intervention Services for Psychosis programs in Nova Scotia and the Psychosis Intervention Early Recovery program in Newfoundland * Diagnosed with a primary psychotic disorder (e.g. schizophrenia, schizoaffective disorder, and unspecified schizophrenia spectrum disorder) * Less than 5 years of psychotic illness * Has problematic alcohol and/or cannabis use (score of 8 or higher on the World Health Organization Alcohol Use Disorders Identification Test (WHO-AUDIT) or Cannabis Use Disorder Identification Test-Revised (CUDIT-R)). Exclusion Criteria: * Current stimulant use disorder
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What it tests

  • Action-Based Cognitive Remediation
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Where

2 sites
Psychosis Intervention Early Recovery program
St. John's, Canada
Nova Scotia Early Psychosis Program
Halifax, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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