๐ŸŒ EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

UHF ECG in LBBB and Response to CRT Prediction

RecruitingNAAges 18 Years - anyAllFaculty Hospital Kralovske Vinohrady
NCT07057544 on ClinicalTrials.gov โ†—
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

The main objective of the project is to demonstrate that in patients with heart failure and QRS complex of nonRBBB morphology lasting over 130 ms, UHF-ECG can differentiate patients with trueLBBB from IVCD better than existing approaches based on the assessment of QRS complex morphology and duration from 12-lead ECG. Another goal of the proposed study is to demonstrate that trueLBBB patients will benefit more from CRT using left bundle branch pacing than from CRT using biventricular pacing. The final aim of the project is to demonstrate that the echocardiographic and clinical response in patients with intraventricular conduction disturbance will be dependent on the degree of reduction in ventricular dyssynchrony after CRT.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * HF due to ischemic or non-ischemic cardiomyopathy * known coronary angiography * NYHA II-IV * LVEF โ‰ค40% * non-RBBB QRSd lasting \>130 ms (by automated measurement) * proximal LBBB proved by an invasive EP study or non-invasive dyssynchrony assessment in case such a method is confirmed to be non-inferior to an invasive EP study during the project Exclusion Criteria: * Age ห‚18 years * heart failure from reversible causes * Moderate to severe aortic stenosis * pregnancy * active myocarditis * hypertrophic cardiomyopathy * cardiac valve surgery in the last three months * myocardial infarction, PCI, or CABG in the last three months * severe valvular disease requiring intervention * severe atherosclerotic disease of the aorta and/or femoral arteries * life expectancy ห‚1 year * known medical condition or contraindication causing potential complications for EP study
๐Ÿ’Š

What it tests

  • LBBAP CRT device implantation
  • BVP-CRT
๐Ÿ“

Where

1 site
Faculty Hospital Kralovske Vinohrady
Prague, Czechia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy