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The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb Salvage

RecruitingNAAges 18 Years - anyAllRoyal College of Surgeons, Ireland
NCT07057817 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The ACHILLS Trial is a multicentre randomised controlled feasibility study comparing partial calcanectomy with and without the use of an antibiotic-impregnated bone graft substitute (Cerament G) for treating calcaneal osteomyelitis, specifically on wound healing rates, re-infection, and overall efficacy in a sample of 30 patients over a one-year period.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 and over * Undergoing partial calcanectomy * Patients with Type1 or Type 2 Diabetes * Patients will be stratified by Pulse status and eGFR Exclusion Criteria: * Patients unfit for surgery * Patients unable to provide informed consent * Patients with overwhelming sepsis that require major amputation * Patients with hypersensitivity to aminoglycosides * Pre-existing calcium metabolism disorder * Severe renal impairment * Patients in whom major limb amputation is deemed inevitable by the treating physician
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What it tests

  • Cerament G
  • Standard Surgical Managment
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Where

1 site
University Hospital Galway
Galway, Ireland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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