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Prospective Clinical Registry of Acute Treatment and Long-term Assessment of Children Meningitis

Recruitingn/aAges any - 17 YearsAllHospital Israelita Albert Einstein
NCT07062445 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective, multicenter, observational clinical registry of pediatric patients with acute infectious meningitis across approximately 20 public and private hospitals in Brazil. The study will include children under 18 years of age with suspected acute infectious meningitis. Data will be collected during hospitalization and post-discharge to evaluate clinical management, treatment and short and long-term outcomes. The study aims to generate real-world evidence on current practices and outcomes to support improvements in national care protocols.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Fever (axillary temperature ≥37.8°C) followed by two or more of the following symptoms\*: severe headache, vomiting, altered consciousness (confusion, drowsiness, or irritability), photophobia (increased sensitivity to light), presence of seizures OR * Fever accompanied by at least one meningeal irritation sign, such as neck stiffness, Kernig's sign, or Brudzinski's sign OR * Sudden onset of fever and appearance of petechial skin rash or hemorrhagic suffusions * In children younger than two years, in addition to the presentations listed above, consider fever with any of the following: irritability, persistent crying, somnolence, or bulging fontanelle. Exclusion Criteria: * Refusal to provide consent for study participation
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What it tests

  • Not listed
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Where

1 site
Hospital Israelita Albert Einstein
São Paulo, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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