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Pulsed Field Ablation vs. Cryoballoon Ablation in Patients With Persistent Atrial Fibrillation

RecruitingNAAges 18 Years - 85 YearsAllKitasato University
NCT07064616 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical study is being conducted to compare two different treatment methods for persistent atrial fibrillation (AF), a common heart rhythm disorder. Atrial fibrillation occurs when the upper chambers of the heart (the atria) beat rapidly and irregularly. This can lead to symptoms like palpitations, shortness of breath, or fatigue, and it increases the risk of stroke or heart failure. Persistent atrial fibrillation means that the irregular heart rhythm continues and does not stop on its own. Treatment often includes a procedure called catheter ablation, where special instruments are used to create small scars in the heart to block the abnormal electrical signals causing the arrhythmia. Currently, two main types of catheter ablation are used in Japan: Cryoballoon Ablation: A technique that uses extreme cold to create scars and isolate the pulmonary veins, which are often the sourc

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 85 years * Diagnosed with PeAF (lasting less than one year or requiring cardioversion) * Eligible for catheter ablation according to current Japanese guidelines * Provided written informed consent Exclusion Criteria: * Paroxysmal or long-standing persistent AF (duration \>1 year)
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What it tests

  • Catheter ablation using pulsed field ablation
  • Catheter ablation using cryoballoon ablation
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Where

1 site
Kitasato University School of Medicine
Sagamihara, Japan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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