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The Effect of Dexmedetomidine on Agitation During Weaning From Mechanical Ventilation

RecruitingNAAges 19 Years - anyAllSohag University
NCT07066605 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the effect of dexmedetomidine on the level of agitation during the weaning process from mechanical ventilation in critically ill patients.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult ICU patients (≥18 years). * On mechanical ventilation ≥24 hours. * Clinically ready for weaning. * Agitation score RASS ≥ +1 during spontaneous breathing trial. * Intubation for at least 4 days: 2 weeks. Exclusion Criteria: * Known hypersensitivity to dexmedetomidine. * Hemodynamic instability (HR \< 50 bpm or MAP \< 60 mmHg). * Neurological impairment affecting level of consciousness. * Pregnancy or lactation.
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What it tests

  • Group A (Dexmedetomidine Group)
  • Group B (Control Group)
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Where

1 site
Sohag University Hospital
Sohag, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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