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โ† Trials
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A Study of AMC6156 in People With Sarcopenia

RecruitingPhase 2Ages 65 Years - anyAllAnimuscure Inc.
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In plain words

What the trial is, and whether it could suit you

This clinical trial aims to find out whether AMC6156 can improve physical function and is safe in older adults with sarcopenia. Participants will take AMC6156 or a placebo daily for 12 weeks, and their movement, strength, and safety will be regularly monitored through tests and checkups.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Voluntary participation with written informed consent * Male โ‰ฅ 65 years or postmenopausal female * Diagnosed with sarcopenia: * ASM \< 7.0 kg/mยฒ (men) or \< 5.4 kg/mยฒ (women) * Plus low handgrip strength or SPPB โ‰ค 9 * MNA screening score โ‰ฅ 8 * Body weight โ‰ฅ 35 kg, BMI between 15-30 kg/mยฒ * Willing and able to follow exercise and nutrition guidance Exclusion Criteria: * Allergy to investigational drug * History of GI bleeding, ulcers, or severe liver/kidney/heart disease * QTc โ‰ฅ 450 ms with symptoms * Severe COPD, uncontrolled diabetes or thyroid disease * Diseases causing cachexia or muscle wasting (e.g., ALS, Parkinson's) * Vitamin D deficiency (\<10 ng/mL), hemoglobin \<10 g/dL * Severe psychiatric disorders or MMSE \< 21 * Inability to walk or recent fracture/surgery affecting mobility * Use of prohibited medications or recent participation in other clinical trials * Investigator deems the subject unsuitable for the study
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What it tests

  • AMC6156 0.1mg
  • AMC6156 0.3mg
  • AMC6156 1.0mg
  • Placebo
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Where

4 sites
CHA Bundang Medical Center
Seongnam-si, South Korea
Seoul National University Bundang Hospital
Seongnam-si, South Korea
Ajou University Hospital
Suwon, South Korea
Seoul National University Hospital
Seoul, South Korea
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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