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Using Cardiac MRI to Predict Outcomes in Patients With STEMI

Recruitingn/aAges 18 Years - 80 YearsAllChinese PLA General Hospital
NCT07072858 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This prospective, multicenter observational study aims to evaluate the prognostic value of a comprehensive set of cardiac magnetic resonance (CMR) imaging parameters in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PCI). The study integrates advanced artificial intelligence (AI) techniques to extract and analyze high-dimensional imaging features from multiple CMR sequences-including cine, strain mapping, and functional sequences-going beyond traditional measures such as infarct size or microvascular obstruction. The primary objective is to identify novel prognostic markers from routinely acquired CMR images that reflect myocardial structure, function, and mechanical deformation (strain), and to assess their association with long-term clinical outcomes. In addition to standard parameters, the study includes a detai

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📋 Eligibility rules (as published)
Inclusion Criteria: * Age between 18 and 80 years Diagnosed with ST-segment elevation myocardial infarction (STEMI), defined as chest pain with ST-segment elevation on ECG and elevated cardiac troponin levels Underwent primary percutaneous coronary intervention (PCI) Able to undergo cardiac magnetic resonance (CMR) imaging within 7 days post-PCI Provided written informed consent Exclusion Criteria: * Contraindications to CMR (e.g., severe claustrophobia, implanted cardiac defibrillators or non-compatible pacemakers) History of revascularization therapy (PCI or CABG) within the previous 6 months Severe valvular heart disease or known cardiomyopathy Presence of bundle branch block or fascicular block that interferes with image interpretation Known allergy to gadolinium-based contrast agents (for those undergoing contrast-enhanced sequences) Estimated glomerular filtration rate (eGFR) \<30 mL/min/1.73m² (if contrast use is anticipated) Pregnant or breastfeeding women
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What it tests

  • Cardiac Magnetic Resonance Imaging (CMR)
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Where

1 site
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Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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