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Evaluation of Right Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Recruitingn/aAges 18 Years - anyAllKanuni Sultan Suleyman Training and Research Hosp…
NCT07073976 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this prospective observational study is to evaluate whether right ventricular (RV) function parameters assessed via transthoracic echocardiography (TTE) can predict weaning success in adult intensive care unit (ICU) patients who are mechanically ventilated. The main questions it aims to answer are: Can the TAPSE (Tricuspid Annular Plane Systolic Excursion) value predict successful extubation? Do other right heart parameters (tricuspid S', RV-FAC, right atrial area, pulmonary valve acceleration time) provide additional prognostic value for weaning outcomes? Participants will: Be adult ICU patients planned for weaning from mechanical ventilation. Undergo transthoracic echocardiography within 2 hours after meeting clinical weaning criteria. Have the following echocardiographic parameters measured: TAPSE, tricuspid S', RV-FAC, right atrial area, and pulmonary valve accelera

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📋 Eligibility rules (as published)
Inclusion Criteria: * Receiving invasive mechanical ventilation in the ICU * Planned extubation (weaning) according to standard clinical criteria * Hemodynamically stable at the time of transthoracic echocardiography (TTE) * Ability to undergo echocardiographic assessment within 2 hours prior to extubation * Informed consent obtained from patient or legal representative Exclusion Criteria: * Known severe tricuspid valve disease or congenital heart disease * Moderate to severe pericardial effusion or cardiac tamponade * Inadequate acoustic window for transthoracic echocardiography * Patients requiring urgent or unplanned extubation * Use of extracorporeal life support (e.g., ECMO) at the time of assessment * Known pulmonary embolism or acute cor pulmonale * Pregnancy
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What it tests

  • Transthoracic Echocardiography (TTE)
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Where

1 site
Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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