🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Evaluation of Left Ventricular Function to Predict Weaning Success in the Intensive Care Unit

Recruitingn/aAges 18 Years - anyAllKanuni Sultan Suleyman Training and Research Hosp…
NCT07075926 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

The goal of this prospective observational study is to evaluate whether left ventricular function parameters assessed via transthoracic echocardiography (TTE) can predict weaning success from mechanical ventilation in adult intensive care unit (ICU) patients. The main questions it aims to answer are: Can the Left Ventricular Outflow Tract Velocity Time Integral (LVOT VTI) predict successful extubation? What is the prognostic value of other echocardiographic measures such as Mitral Annular Plane Systolic Excursion (MAPSE), E/e' ratio, E/A ratio, Mitral Deceleration Time (MDT), and Myocardial Performance Index (Tei index) in forecasting weaning outcomes? Participants will: Be adults receiving mechanical ventilation and scheduled for weaning Undergo transthoracic echocardiography (TTE) within 2 hours after meeting weaning criteria Have the following parameters measured: LVOT VTI, MAPS

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Currently receiving mechanical ventilation in the ICU * Planned extubation after meeting standard weaning criteria * Hemodynamically stable at the time of echocardiographic evaluation * Written informed consent obtained from the patient or legally authorized representative Exclusion Criteria: * Surgery within the previous 24 hours * Presence of significant valvular heart disease or known cardiomyopathy * Inadequate acoustic window for transthoracic echocardiography * Ongoing use of extracorporeal support (e.g., ECMO) * Patients with Do-Not-Resuscitate (DNR) orders or expected to die within 24 hours * Re-intubation planned prophylactically regardless of clinical status * Pregnant patients
💊

What it tests

  • Echocardiographic Assessment
📍

Where

1 site
Health Science University İstanbul Kanuni Sultan Süleyman Education and Training Hospital
Istanbul, Turkey (Türkiye)
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy