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โ† Trials
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Vascular Trial Associated Registry Pilot

RecruitingPhase 4Ages 45 Years - anyAllCorewell Health West
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In plain words

What the trial is, and whether it could suit you

The purpose of this investigator-initiated, multicenter, open label, randomized trial is to evaluate 1 month vs. 6 months of dual antiplatelet therapy (DAPT) in patients undergoing lower extremity endovascular revascularization. We hypothesize that extending dual antiplatelet therapy (DAPT) to six months, compared to one month, will improve patency rates of target vessels following peripheral vascular intervention (PVI) without significantly increasing complications, particularly bleeding events.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age greater than or equal to 45 at time of enrollment * Patient is scheduled for a PVI or has recently had a PVI in the last 30 days * Patient data is being submitted to Fivos, who is acting as the data collection subcontractor for the VQI-PVI registry. * Atherosclerotic vascular disease Exclusion Criteria: * Patients who cannot consent for themselves * Allergy to Clopidogrel * Patients unable to stop clopidogrel for other medical reasons * Patients on dual pathway inhibition (DPI) with low dose rivaroxaban (2.5mg twice a day) that are unable to stop these medications * Allergy to aspirin * Nonatherosclerotic vascular disease * Patients undergoing open bypass at the same time as the peripheral transcutaneous angioplasty * Patients with high bleeding risk (HBR) defined as: * History of major bleeding, active bleeding disorder, severe renal impairment (CrCl \<30), concurrent anticoagulation, platelet count \<100,000 * Recent stroke (within 6 months) * Current warfarin therapy or full dose therapeutic direct oral anticoagulants (DOAC). * Patients unwilling or unable to comply with standard of care follow-up visits * Pregnant women * Prisoners
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What it tests

  • Clopidogrel (Plavix) Pharmacogenetic Test Reagents
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Where

2 sites
Henry Ford Hospital
Detroit, United States
Corewell Health West
Grand Rapids, United States
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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