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EACVI Study on Multimodality Cardiovascular Imaging of Inflammatory Cardiovascular Diseases

Recruitingn/aAges 18 Years - anyAllAssistance Publique - Hôpitaux de Paris
NCT07077304 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Inflammatory Cardiovascular Diseases and Autoimmune Rheumatic Diseases (ICARDs) encompass cardiovascular involvement in connective tissue diseases, vasculitis, and primary inflammatory cardiac processes affecting all layers of the heart. ICARDs are associated with increased cardiovascular morbidity and mortality, independently of traditional risk factors, via multiple pathophysiological mechanisms. Diagnosis and prognosis are challenged by the heterogeneity of clinical presentations. Multimodality cardiovascular imaging - including cardiovascular magnetic resonance (CMR), transthoracic echocardiography, and positron emission tomography (PET) - plays a central role in detecting and characterizing inflammatory involvement, and may offer prognostic insights. Given the limited data on the diagnostic and prognostic utility of these imaging modalities in ICARDs, the EACVI-INFLAME study aims

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥ 18 years 2. Ability to provide informed non-opposition 3. Referred for a CMR and/or nuclear imaging exam AND a suspicion of one of the following ICARDs : 1. Suspected Myocarditis (acute or chronic, and whatever the aetiologies) 2. Suspected Myocardial Infarction with Non-Obstructive Coronary Arteries (MINOCA) 3. Suspected Tako-Tsubo 4. Suspected Pericarditis (acute or chronic, and whatever the aetiologies) 5. Suspected Connective tissue disease with cardiovascular involvement: * Systemic sclerosis * Systemic lupus erythematosus * Antiphospholipid syndrome * Idiopathic inflammatory myopathies * Rheumatoid arthritis, spondylarthritis 6. Suspected Vasculitis with cardiovascular involvement: * Small-vessel vasculitis (ANCA…) * Large vessel vasculitis (Behcet disease, Takayasu…) 7. Suspected Inflammatory disease with cardiovascular involvement: * Sarcoidosis * Still disease Exclusion Criteria: 1. Inability to provide non-opposition 2. History of heart transplant
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What it tests

  • observational study
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Where

1 site
Assistance Publique Hôpitaux de Paris, Paris, île de France 75010
Paris, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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