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A Study to Evaluate Splenectomy on Debridement for Acute Necrotizing Pancreatitis With Pancreatic Sinistral Portal Hypertension

RecruitingNAAges 18 Years - 75 YearsAllZhejiang University
NCT07080697 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a prospective, single-center, randomized controlled trial focusing on patients with acute necrotizing pancreatitis (ANP) complicated by pancreatic sinistral portal hypertension (PSPH). The study aims to study the impact of total splenectomy on the debridement efficacy, perioperative recovery, and prognosis of patients with ANP complicated by PSPH.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 75 years. 2. Acute necrotic pancreatitis complicated by pancreatic sinistral portal hypertension. 3. Patients undergoing open debridement for infected pancreatic necrosis Exclusion Criteria: 1. Patients with pre-existing heart, lung, liver, kidney, or other organ failure prior to acute pancreatitis (AP). 2. Patients with pre-existing conditions such as cirrhosis that may lead to portal hypertension prior to AP. 3. Patients with pre-existing hematological diseases prior to AP. 4. Patients undergoing laparoscopic or nephroscopic debridement.
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What it tests

  • Splenectomy
  • Control
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Where

1 site
First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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