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โ† Trials
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Physical Fitness and Hot Executive Function in Alzheimer's Risk

Recruitingn/aAges 50 Years - 70 YearsAllNational Taiwan Normal University
NCT07081269 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ฮต4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.

Sign in to get the eligibility rules as simple questions to take to your doctor.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Age 50-70. * Able to engage in fitness testing. * Normal vision or corrected-to-normal vision. Exclusion Criteria: * Suffering from cardiopulmonary-related diseases. * Suffering from cognitive, neurological or psychiatric disorders (e.g., dementia, Parkinson's disease, epilepsy, depression, schizophrenia, etc.). * Suffering from infectious diseases (e.g., hepatitis, human immunodeficiency virus or Creutzfeldt-Jakob disease). * Having a history of drug or alcohol abuse. * Having colour vision deficiency (e.g., colour blindness). * Having a family history of aneurysm. * Taking medications that affect brain function.
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What it tests

  • observation alone
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Where

1 site
National Taiwan Normal University
Taipei, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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