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โ† Trials
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Efficacy of LcS-Fermented Milk on Constipation-Related Symptoms in Filipino Adults

RecruitingNAAges 18 Years - 59 YearsAllUniversity of Santo Tomas
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In plain words

What the trial is, and whether it could suit you

The primary purpose of this study is to investigate whether the consumption of a probiotic drink (with Lacticaseibacillus paracasei strain Shirota (LcS)) relieves constipation-related symptoms of Filipino adults, specifically its effect on stool consistency, frequency, and duration, and on gastrointestinal discomfort.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Filipino adult male or female aged 18 to 59 years old * Apparently healthy adults with constipation-related symptoms of hard to lumpy stools (Bristol Stool Form Scale 1-2) in 25% or more of defecations in a week * With cold storage at home Exclusion Criteria: 1. Habitual intake of food items containing probiotics and prebiotics as food supplements (previous 3 months, at least three times per week) 2. Constipation due to organic or neurologic origin 3. High fiber intake (\>30 g/day) 4. Pregnant or lactating 5. Allergy to dairy products and/or lactose intolerance 6. Use of laxatives, anticholinergics and medications for constipation or diarrhea within the past three months 7. Use of antibiotics within the past two weeks 8. Presence of chronic diseases such as diabetes mellitus and its complications, cardiovascular diseases, kidney problems 9. GI condition that may interfere with the evaluation of the outcome such as hemorrhoids, intestinal obstruction and inflammatory bowel diseases 10. Recent history of any gastrointestinal surgery 11. Have pre-existing medical conditions like hypo- or hyperthyroidism and congenital abnormalities 12. Participation in another study with test product two months prior the study
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What it tests

  • Experimental: Probiotic with LcS
  • Control
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Where

1 site
University of Santo Tomas
Manila, Philippines
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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