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โ† Trials
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Effect of Vitamin D3 Supplementation on Cardiac Autonomic Nerve Function in Male Parkinson's Disease Patients With Hypovitaminosis D

RecruitingNAAges 51 Years - 70 YearsMaleBangladesh Medical University
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to see the effect of vitamin D3 supplementation on cardiac autonomic nerve function in male Parkinson's disease patients with hypovitaminosis D Main questions it aims to answer are: 1. Does vitamin D improves heart rate variability(HRV) in male Parkinson's disease patients ? 2. Does vitamin D improves cardiac autonomic nerve function in male Parkinson's disease patients ? It is a self control trial. Vitamin D3 deficient Parkinson's disease participants will a. undergo through baseline HRV test b. Then they will take vitamin D3 capsule 50000 IU once in a week for 8 consecutive weeks c. Then after intervention with vitamin D supplementation post interventional HRV will be done. Researcher will compare pre intervention(pre test) and post intervention(post test) value of HRV

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
IInclusion criteria: * Male patients with of Parkinson's disease diagnosed by neurologist with unilateral or bilateral involvement and mild to moderate disability according to Hoehn and Yahr (H-Y) scale (I-III) * Age: 51-70 years * BMI: 18.5-24.9 kg/m2 * Vitamin D3 deficient or insufficient * On Levodopa medication Exclusion criteria: 1. Patients with a history of drug abuse including alcoholism. 2. Patients on following drugs will be excluded- * Antioxidant vitamin supplements * Lipid lowering medications * Antihypertensive drug * Anti-arrhythmic drug * Sedatives 3. All patients with the history of or clinical manifestation of currently suffering from following diseases \& condition will be excluded * Severe Cardiovascular disorders * Severe neurological disorders * Severe Respiratory disorders * Severe Renal insufficiency (S. Creatinine \> 1.5 mg/dl, Acute or chronic kidney disease) * Severe Endocrine disease * Severe Arthritis * Severe Liver diseases * Severe Neoplastic disease * Severe Psychiatric disorder * Current use of iron, zinc, calcium, magnesium and multivitamin supplementation * Already performing yoga or breathing exercise * Hypercalcemia
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What it tests

  • Vitamin D
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Where

1 site
Bangladesh Medical University
Dhaka, Bangladesh
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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